A 2022 Toyota Sienna with a pull-behind camper beside a mountain lake and trees


  • Choose available AWD on any Sienna model.
  • Switch between various drive modes in the Sienna, including Normal, ECO, and more.
  • Only the Sienna has a hybrid engine that makes the Odyssey's estimated fuel economy ratings pale in comparison.

Get a van that handles well in the rain and efficiently tackles miles of driving.

Driving Made Easy

For extra reassurance in inclement weather, the Sienna has All-Wheel Drive available on all trim levels. The Odyssey has nothing other than the standard Front-Wheel Drive drivetrain option.

While the Odyssey does have a Snow Mode driving option for better performance in wintery conditions, the Sienna has available AWD and Normal, ECO, EV, and Sport drive modes.

It's one thing to have a vehicle with available AWD and it's another to have a van that has both available AWD and a standard hybrid engine. No matter the drivetrain you choose, all Sienna models have a hybrid engine. The Sienna FWD has an EPA-estimated 36/36/36 (city/highway/combined) MPG rating and the AWD versions have an EPA-estimated 35/36/35 (city/highway/combined) MPG rating. The competition doesn't even come close with an EPA-estimated 19/28/22 (city/highway/combined) MPG rating across the Odyssey lineup.

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A Sienna being parallel parked.


  • You get similar active safety features with the Sienna's Toyota Safety Sense 2.0 (TSS 2.0) and Odyssey's Honda Sensing Safety and Driver Assistive Technologies.
  • Blind Spot Monitor (BSM) and Rear Cross-Traffic Alert (RCTA) with Rear Cross-Traffic Braking (RCTB) are only standard with the Sienna.
  • Get an additional LATCH position with the Sienna 8-Passenger.

Safety remains a top priority with the 2022 Sienna. Active and passive safety features are included with both the Sienna and Odyssey.

Standard Safety Features

The 2022 Sienna comes with Toyota Safety Sense 2.0 (TSS 2.0), which includes a whole list of active safety features. You can expect a Pre-Collision System with Pedestrian Detection (PCS w/PD), Lane Departure Alert with Steering Assist (LDA w/SA), Lane Tracing Assist (LTA), Automatic High Beams (AHB), Full-Speed Range Dynamic Radar Cruise Control (DRCC), and Road Sign Assist (RSA).

Comparatively, Honda Sensing Safety and Driver Assistive Technologies include similar features like the Collision Mitigation Braking System™ (CMBS™), Lane Keeping Assist System (LKAS), Lane Departure Warning (LDW), Adaptive Cruise Control with Low-Speed Follow (ACC), Auto High-Beam Headlights, and Traffic Sign Recognition System (TSR) standard with the Odyssey.

For the additional Blind Spot Information System (BSI) with Cross Traffic Monitor, you'd have to go a model above the Odyssey LX, while Blind Spot Monitor (BSM) and Rear Cross-Traffic Alert (RCTA) with Rear Cross-Traffic Braking (RCTB) are standard on all Sienna models.

Help keep your kiddos secured in the Sienna 8-Passenger, which comes with Five Lower Anchors and Tethers for Children (LATCH) positions for car seats or booster seats. These include lower anchors on all three second-row seats plus LATCH positions on passenger-side and center third-row seats. The Odyssey has Lower Anchors (2nd-Row All, 3rd-Row Passenger-Side) and Tether Anchors (2nd-Row All, 3rd-Row All). You get the extra center third-row anchor with the Sienna.

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A 2022 Sienna interior with a view of the beach through an open door.


  • Both the Sienna and Odyssey have adaptive second rows to help make getting in and out of your van a lot easier.
  • The Sienna includes three-zone climate control so everyone can adjust the temperature the way they want.
  • Get more standard connectivity options with the 2022 Sienna.

Find out how the Sienna's interior features help make your ride a little more comfortable and enjoyable for all.

Comfort and Convenience

Get easy access to the third-row seating with the Sienna XLE 7-Passenger super-long slide feature. Or, slide the second-row seat all the way back for an easier time getting the kids out of their car seats. The Sienna’s seating options also allow for versatility in sharing additional leg room or storage in the Sienna. Magic Slide® 2nd-Row Seats in the Odyssey EX and higher offer unique configuration options. You can take out the second-row middle seat to push the two outer seats together, making a clear path to the third row. Or, slide the seat forward to make the second-row seats within reach of the first row.

To help keep everyone comfortable, the Sienna comes standard with three-zone automatic climate control with air filter, individual temperature settings for the driver, front passenger and rear-seat passengers, and a separate rear digital control panel. Four-zone automatic climate control is standard on the XLE and higher. Comparatively, the Odyssey comes standard with an Automatic Climate Control System. The Tri-Zone Automatic Climate Control System with 2nd-Row Controls, Humidity Control and Air Filtration is only available on the Odyssey EX or higher.

Moving from comfort to convenience, you get standard hands-free phone capability and music streaming via Bluetooth® wireless technology and a SiriusXM® 3-month Platinum Plan trial subscription with the all 2022 Sienna models. Plus, play your favorite music through Android Auto™, Apple CarPlay®, and Amazon Alexa compatibility. Every Honda Odyssey has Bluetooth® HandsFreeLink® and Streaming Audio standard, but Apple CarPlay®, Android Auto™, and SiriusXM® Radio are only available on the Odyssey EX and higher.

Stay connected and fully charged with seven USB ports across all three rows standard in the Sienna. The Odyssey LX has one center console USB Charging Port and one center console USB Audio Interface. Five USB ports are the max for the Odyssey Touring and Elite.

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Conclusion: Sienna vs. Odyssey

When you have more passengers on board, safety and convenience features are key to helping keep everyone happy and healthy. The Toyota Sienna and Honda Odyssey have seating for the whole family, but the Sienna has more standard features.

One feature you can expect on all Sienna models is a hybrid engine that makes for a better road trip experience with an EPA-estimated 36/36/36 (city/highway/combined) MPG rating. The Odyssey has an EPA-estimated 19/28/22 (city/highway/combined) MPG rating for all trims.

Don't struggle to get the kids in and out of their car seats with the Sienna super-long-slide feature on the 7-Passenger XLE and higher. The Odyssey does not have this ability.

With better estimated MPG ratings, more standard multimedia options, and available AWD, it's easy to see why the Sienna won the Kelley Blue Book® 2021 Best Buy Award for a minivan and ideal choice for you and your family.

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  • Choose the 2022 Sienna and get a hybrid engine with optimal estimated fuel efficiency ratings.
  • The Sienna's super-long-slide seat feature will help you get the kids of the car with ease.
  • For added confidence on the road, the Sienna has an available AWD drivetrain.